Avodart is currently available via most pharmacies, however, the questions remain: How much should you take? Is it safe or will it cause side effects? Where are you going to get a prescription for it? We’ve got the latest information on these topics, as well as some new insight into the Phase III trials here…

Avodart is the brand name for the latest BPH drug that also showed results in treating hair loss (in men only) in Clinical Trials. The only other drug that has performed quite as well under the scrutiny of clinical trials has been Propecia, so all attention is on Avodart as it debuts in the Pharmacies of the United States this month.

AVODART (dutasteride) is a synthetic 4-azasteroid compound that is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5a-reductase (5AR), an intracellular enzyme that converts testosterone to 5a-dihydrotestosterone (DHT).

Dutasteride is chemically designated as (5a,17b)-N-{2,5 bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-1-ene-17-carboxamide. The empirical formula of dutasteride is C₂₇H₃₀F₆N₂O₂, representing a molecular weight of 528.5 with the following structural formula:

Dutasteride is a white to pale yellow powder with a melting point of 242° to 250° C. It is soluble in ethanol (44 mg/mL), methanol (64mg/mL), and polyethylene glycol 400 (3mg/mL), but it is insoluble in water.

AVODART Soft Gelatin Capsules for oral administration contain 0.5 mg of the active ingredient dutasteride in yellow capsules with red print. Each capsule contains 0.5 mg of dutasteride dissolved in a mixture of mono-di-glycerides of caprylic/capric acid and butylated hydroxytoluene. The inactive excipients in the capsule shell are gelatin (from certified BSE-free bovine sources), glycerin, and ferric oxide (yellow). The soft gelatin capsules are printed with edible red ink.

Avodart - Dutasteride - is a 5alpha-reductase inhibitor that inhibits both types 1 and 2 isozymes of 5alpha-reductase, the enzyme responsible for converting testosterone to dihydrotestosterone in the prostate and other tissues. Dihydrotestosterone is the primary cause of prostate growth and has been proven to play a key role in the development and progression of benign prostatic hyperplasia. Avodart has been investigated in three multicenter studies involving 4325 men aged 50 years and above with benign prostatic hyperplasia. Data from these two-year, placebo-controlled studies demonstrated that Avodart 0.5 mg once daily reduced the risk of both acute urinary retention and the need for benign prostatic hyperplasia-related surgical intervention, improved benign prostatic hyperplasia-related symptoms, decreased prostate volume and increased maximum urinary flow rates.

Q. Is it okay to take Avodart one day and Prostate Power Rx the next? I get Avodart side effects when I use it daily but it does help my prostate symptoms.
A. Herbs are not as potent as drugs. One option, if your doctor agrees, is to alternate every other day taking Avodart one day and prostate power the next, or something similar to this. This way you get herbs that support your prostate while the Avodart helps the symptoms, but have less side effects since a lower amount is being used.If you want to consult one of our specialists please follow the link for the free consultation