Dutasteride results, clinical test and more
Regrowth - A total of 18 posters.
Plenty of people have regrowth already in just about 1 month, particularly in the form of tiny small hairs on the temples. The majority reported vellus hairs growing on the temples, a couple reported regrowth in areas that have been bald for years, and many said existing vellus hairs are darkening and there are definitely signs that hairs are becoming thicker and switching into terminal hairs. It appears that for the time being, the positive feedbacks are predominantly about regrowth on the temples, only a couple mentioned regrowth on the crown.
MAXIMUM EFFECT
According to Avodart or dutasteride’s prescribing information, the maximum effect of dutasteride can be observed within 1 to 2 weeks. “After 1 and 2 weeks of daily dosing with dutasteride 0.5mg, median serum DHT concentrations were reduced by 85% and 90% respectively.” It was further reported that test patients treated with a daily dosage of 0.5mg dutasteride for 2 years, the median decrease in serum DHT concentration was over 92% for both year 1 and year 2 of the 2-year trial.
Dutasteride is the first dual inhibitor of both 5α-reductase Types 1 and 2 isoenzymes, with efficacy and safety proven in 3 randomized placebo-controlled trials, each 2 years in duration. The current report demonstrates that longer-term treatment over 48 months with dutasteride results in continuing improvements in urinary symptoms and flow rate, and further reductions in total and transition zone volume of the prostate in men with symptomatic benign prostatic hyperplasia (BPH). The reduction in risk of acute urinary retention and BPH-related surgery, seen in the double-blind phase, was durable over the 4-year term of the studies. The incidence of new onset adverse events remained low during the open-label extension phase, and less than 1% of patients discontinued therapy due to adverse events. These findings combined establish that the disease-modifying benefits of dutasteride are durable in long-term treatment. Dutasteride was also well tolerated in long-term use, with no new safety issues emerging over 4 years of treatment.
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